• Women who are old, and who has amenorrhea for 6 months
• Patients with vertebral fractures or osteoporosis on X-ray images
• Patients taking certain medications (steroids, anticonvulsants, some cancer drugs)
• patients who has Part hyperthyroidism, hyperthyroidism
• Multiple rheumatoid arthritis patients
• Patents who have Small and thin bones and family history of osteoporosis
• Starvation of anorexia nervosa and psychotic person
• Patients who have premature menopause, calcium intake decreasing
• Patents who are Smoking, Sitting lifestyle and job
• Patents who are impaired intestinal absorption, or male hormone is degraded